Mitigating effect ofAvicenna marinaon indomethacin induced gastric ulcer in male albino rats

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چکیده

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Effect of Feronia elephantum (Corr) Fruit Pulp Extract on Indomethacin-induced Gastric Ulcer in Albino Rats

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Effect of glucocorticoids on indomethacin-induced gastric ulcer in the adult male albino rat – histological, morphometric and electron microscopy study

INTRODUCTION Indomethacin is a non steroidal anti-inflammatory drug (NSAID) which is capable of producing injury to gastric mucosa. To prevent of NSAID-induced gastropathy, it is important to evaluate the risk factors. One of them is steroid. The aim is to study time dependent effects of glucocorticoids (GC) on indomethacin induced gastric ulcer. MATERIAL AND METHODS Forty-nine albino rats we...

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Gastric mucosal cellular changes induced by indomethacin (NSAID) in male albino rats.

Indomethacin (2 mg/100 g body weight), induces haemorrhagic gastric ulcers in albino rats. The incidence and severity of ulceration increased with starvation period. Indomethacin caused little or no effect on the cellular and the nuclear diameter of parietal and chief cells while reduction was observed in mucus and endocrine cells. The effect was enhanced with increased duration of starvation. ...

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ژورنال

عنوان ژورنال: Egyptian Journal of Basic and Applied Sciences

سال: 2016

ISSN: 2314-808X

DOI: 10.1016/j.ejbas.2016.01.004